■Foreword

Towards Real Science that Can Reveal Reality

Yoshio Matsui

■Feature Articles: Tumor Initiating Cells and Their Regulation

Tumor-Initiating Cells and Their Dynamic State

Eiichi Morii

Markers for Tumor-Initiating Cells

Eiichi Morii and Jun-ichiro Ikeda

Bone Marrow-Derived Mesenchymal Stem Cells Provide an Advantageous Tumor Microenvironment for the Restoration of Gastric Cancer Stem Cells

Shuho Semba

Vascular Niche for Cancer Stem Cells and Angiogenesis

Nobuyuki Takakura

Immunotherapy Targeting Cancer Stem-Like Cells

Yoshitaka Michifuri, Yoshihiko Hirohashi, Hiroyoshi Hiratsuka and Noriyuki Sato

■Reviews

Valence Electron Spectroscopy Based on Electron Microscopy

Masami Terauchi

Newly Bioactive Peptide “Kisspepitin” and Its Role for the Neuronal Regulation System for Reproduction～New Aspect of Hypothalamus-Pituitary-Gonad (HPG) Axis～

Hitoshi Ozawa, Ken Takumi, Nobuhiko Sawai, Kinuyo Iwata, Ryo Nakane and Norio Iijima

■Lectures

Generalization of Paraxial Trajectory Method for the Analysis of Non-Paraxial Rays: Simulation Program G-optk for Electron Gun Characterization

Shin Fujita

Novel Single-Neuron-Tracing Method Using Sindbis Viral Vectors

Eriko Kuramoto, Takahiro Furuta, Hiroyuki Hioki, Fumino Fujiyama and Takeshi Kaneko

■Researches Today

Disital Tracing in Neuro-Morphology

Emi Kiyokage, Eiji Notsu, Takahiko Akagi and Kazunori Toida

Atmospheric Scanning Electron Microscopy (ASEM) of Dynamic Phenomena of Materials in Liquid

Mitsuo Suga, Hidetoshi Nishiyama, Yuji Konyuba, Yoshiyuki Watanabe, Shinnosuke Iwamatsu and Chikara Sato

Atomic Resolution Secondary Electron Imaging with Aberration Corrected Scanning Transmission Electron Microscope

Hiromi Inada, Keiji Tamura, Yuya Suzuki, Mitsuru Konno and Kuniyasu Nakamura

■Conference Reports

Report on 40^th Annual Meeting of Society for Neurosciece

Kazunori Toida

■Staff Commentary

Hiroki Kurata