MICROSCOPY Vol.43▶No.2 2008
â– Feature Articles: Re-evaluation of fibroblasts and fibroblast-like cells: newer aspects

Role of corneal fibroblasts in infection

Teruo Nishida

Abstract: Corneal fibroblasts are responsible for the homeostasis of the transparent cornea through synthesis and degradation of collagen fibrils. Under the pathological conditions, such as infection, corneal fibroblasts play roles as a control tower to recognize the microbial pathogen and to modulate the secretion and activation of MMPs.

Key Words: Cornea, fibroblasts, Infection, Ulcer, MMP