MICROSCOPY Vol.43▶No.4 2008
â– Feature Articles: Application of High Voltage Electron Microscopy for Biomedical Science

Observation of Cell Organelles with HVEM

Toru Noda

Abstract: High voltage electron microscopy (HVEM) is one of powerful tools to be able to visualize the three-dimensional structures of cell organelles. However, this technique cannot be effectively realized without histochemical techniques that give electron densities on various cell organelles selectively. In this section, various staining techniques used for HVEM so far and their applications will be explained showing the examples.

Key words: high voltage electron microscopy, histochemistry, cell organelles