MICROSCOPY Vol.46▶No.2 2011
â– Feature Articles: Tumor Initiating Cells and Their Regulation

Markers for Tumor-Initiating Cells

Eiichi Morii and Jun-ichiro Ikeda

Abstract: Tumors are consisted of monoclonal cells, but the individual cells in tumors show various phenotypes. Recently, it has been reported that tumors are derived from a limited population of cells, called tumor-initiating cells, that are resistant to chemo-radio therapies and are tumorigenic. Tumor-initiating cells are considered to cause recurrence and metastasis of tumors. Here, we summarized the markers characteristic to tumor-initiating cells

Key words: tumor-initiating cells, side-population, aldehyde dehydrogenase