KENBIKYO Vol.52▶No.3 2017
■Researches Today

Preparation and Application of Organosilica Nanoparticles

Michihiro Nakamura

Abstract: Novel microscopic observation techniques that applied nanotechnology are developing. We developed novel functional nanoparticles termed as organosilica nanoparticles. The organosilica nanoparticles were applied to biomedical research. We investigated macrophage uptakes using fluorescent organosilica nanoparticles. We could evaluate the macrophage uptakes using fluorescent microscopy and electron microscopy, and found novel characteristics of them functionally and structurally. Further multifunctionalization of nanoparticles provide new progress of microscopic observation techniques.

Key words: Organosilica nanoparticles, fluorescent nanoparticles, fluorescent microscopy, electron microscopy