■ Foreword

In an Era of Change

Yoshihiko Hirotsu

■ In Memoriam

Memorial Address for Professor Hiroshi Fujita

Hirotaro Mori

■ Feature Articles: High-resolution Structural Analysis of Biological Macromolecules

Recent Studies on High-resolution Structural Analysis of Biological Macromolecules

Kaoru Mitsuoka

EM Study of Supramolecules Involved in the Life Cycle of Rice Dwarf Virus

Kenji Iwasaki, Naoyuki Miyazaki, Sumie Katayama and Toshihiro Omura

Plug Gating Mechanism of Gap Junction Channels Revealed by Electron Crystallography

Atsunori Oshima

High Resolution Structural Analysis of the Dynein-Microtubule Complex

Keiko Hirose and Hironori Ueno

Smallest Structure of Biological Macromolecular Complex Revealed by Single Particle Image Analysis

Takayuki Kato, Russell P. Goodman, Christoph M. Erben, Andrew P. Turberfield and Keiichi Namba

■ Reviews

Application of Spin Polarized Electrons for Electron Microscopes

Tsutomu Nakanishi

Water Channel Aquaporins in the Kidney and Salivary Glands

Toshiyuki Matsuzaki, Kuniaki Takata and Hitoshi Ozawa

■ Lectures

Morphological Studies of Functional Molecules Building Mammalian Sperm Flagella

Hiroshi Iida, Hitoshi Kurio and Takane Kaneko

Three-dimensional Imaging Characteristics in Imaging Optical Systems

Takashi Ikuta

■ Researches Today

Melanin Pigment Cells: Their Localization and Functional Divergence

Nagaharu Tsukiji, Shigeyuki Uehara, Daisuke Nishihara, Sei-ichi Ishiguro and Hiroaki Yamamoto

Cleavage Signal Induced by the Mitotic Spindle; Insights from Live Cell Imaging

Keiju Kamijo

XEDS Analysis of Thin-foil Specimens in AEM: Current Status and Developments

Masashi Watanabe

AFM Characterization for Mechanical Properties of Polymeric Materials

Ken Nakajima, So Fujinami and Toshio Nishi

Dynamical Observations of Crystal Growth and Phase Transition by Surface Electron Microscopy

Hiroki Hibino

■ Staff Commentary

Hitoshi Ozawa